Ingredients Glossary

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Term Definition
Nicotinamide riboside chloride
  • To replenish NAD declining due to aging
  • To increase the healthy lifespan
  • To live younger for longer
  • To boost cellular NAD+ levels in mature adults

Nicotinamide riboside is a form of vitamin B3 also know as Niagen. It is as a precursor for nicotinamide adenine dinucleotide (NAD+), a coenzyme needed for metabolism, energy production and repairing DNA damage.1,3

In recent years NAD+ has been heavily researched,. A significant reduction in intracellular NAD+ levels is associated with aging and contributes to the development of chronic cardiovascular, neurodegenerative, and metabolic diseases. It is of particular importance to maintain optimal levels of NAD+ in cells with high energy consumption, particularly in the brain. 2

 

 References

1. Johnson S, Imai SI. NAD + biosynthesis, aging, and disease. F1000Res. 2018 Feb 1;7:132. doi: 10.12688/f1000research.12120.1. PMID: 29744033; PMCID: PMC5795269.

2. Kolotyeva NA, Groshkov AA, Rozanova NA, Berdnikov AK, Novikova SV, Komleva YK, Salmina AB, Illarioshkin SN, Piradov MA. Pathobiochemistry of Aging and Neurodegeneration: Deregulation of NAD+ Metabolism in Brain Cells. Biomolecules. 2024 Dec 6;14(12):1556. doi: 10.3390/biom14121556. PMID: 39766263; PMCID: PMC11673498.

3. Cercillieux A, Ciarlo E, Canto C. Balancing NAD+ deficits with nicotinamide riboside: therapeutic possibilities and limitations. Cell Mol Life Sci. 2022 Aug 2;79(8):463. doi: 10.1007/s00018-022-04499-5. PMID: 35918544; PMCID: PMC9345839.

 

Products that contain Nicotinamide riboside chloride